The NFL’s Week 12 schedule includes multiple divisional matchups such as Cowboys vs. Commanders (-10.5, 45), Broncos vs. Raiders (+5.5, 41) and Cardinals vs. Seahawks (+1, 47.5). These rivalry games can end up closer than expected, one of the NFL betting trends to keep in mind when placing your NFL Week 12 bets. Packers vs. 49ers (+5.5, 44.5) will take place on Sunday, and 49ers quarterback Brock Purdy has been ruled out with a shoulder injury. However, San Francisco will get tight end George Kittle back from a hamstring injury. There is another type of rivalry that will take place on Monday Night Football, a sibling rivalry. The Harbaughs will be on the opponent’s sidelines, as the Ravens are 2.5-point favorites over the Chargers in the Week 12 NFL odds, one of the narrowest spreads of the week in the NFL. The over-under for that game is 51, four more than the first game.
John and Jim Harbaugh have faced each other twice before, including in Super Bowl XLVII. John’s Ravens won and covered in the previous two meetings. Should what happened more than a decade ago affect your NFL Week 12 predictions? All of the updated NFL Week 12 lines are listed below, and SportsLine’s advanced computer model has all the NFL betting tips and NFL predictions you need to make the best Week 12 NFL picks. NFL now.
The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model entered Week 12 of the 2024 NFL season with an incredible 20-8 betting streak on top-rated NFL picks this year. Longer term, he is on a 200-136 streak on top-rated NFL picks dating back to the 2017 season and a 54-29 streak on top-rated NFL picks dating back to Week 7 of 2022.
The model has also ranked in the top 10 on NFLPickWatch four of the last six years in straight NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who follows sports betting and betting apps has made strong profits.
Now, you’ve turned your attention to the latest Week 12 NFL odds and NFL betting lines and set betting picks for every NFL matchup. Head here to see each pick.
Top Week 12 NFL Predictions
We can tell you that one of the model’s strongest picks for NFL Week 12 is the Bears (+3.5, 39.5) covering the spread at home against the Vikings. No team has a better home record than the Bears (4-1), and this isn’t a one-year thing. Chicago has the best home record against the spread (8-3-2) since the start of last season. Meanwhile, the Vikings have failed to cover two of their last three road games. Additionally, after starting the year a perfect 5-0 against the spread (ATS), the Vikings are just 2-3 ATS in their last five games overall.
The Bears’ offense showed new life under a new offensive coordinator in Sunday’s loss to Green Bay when Chicago scored 19 points after averaging just nine points in its previous three games. On defense, the Bears could also take advantage of a sloppy Vikings offense that has committed the fifth-most turnovers this season. Chicago has gone three straight games without a turnover and ranks third in the all-important turnover differential statistic (plus nine). SportsLine’s advanced model has the Bears (+3.5) covering nearly 60% of the time. See what other equipment to choose here.
Another of your NFL Week 12 predictions: the Eagles (-3, 49) cover on the road against the Rams on Sunday Night Football. Philadelphia has won seven of the last eight meetings with the Rams, and Philadelphia comes into this matchup with five straight road wins against the Rams. This season, Philadelphia has the best road ATS record in the league (5-1), is on a six-game winning streak, and the Eagles have covered four of their last five games. Eagles receiver DeVonta Smith has been out of practice this week with a hamstring injury.
After having the second-worst pass defense last season, the Eagles have done a 180 and are now the second-best passing defense. That will make it difficult for Los Angeles to move the ball because Los Angeles already ranks 30th in yards per rushing attempt and doesn’t seem to have much success in the passing game against Philadelphia’s solid defense. The Rams are also in the bottom eight in both third-down conversion percentage and red zone scoring. With these factors, the Eagles (-3) are predicted to hit more than 50% of the simulations, and the model also says the Minus (48) will hit more than 50% of the time. See what other equipment to choose here.
How to make Week 12 NFL picks
The model also made a decision on who wins and covers in all other games on the NFL’s Week 12 schedule and just revealed three coveted A-rated picks against the spread, potentially netting him a big payday. You can only get all the picks for each game at SportsLine.
So what NFL picks can you confidently make and what three A-rated picks should you lock in now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a tested computer model that has returned more than $7,000, and find out.
Week 12 NFL Betting Odds, Lines and Spreads
Get Week 12 NFL Picks at SportsLine
