Cowboys vs Eagles is usually a marquee game, but given Dallas’ struggles in 2024, other Sunday games may draw more interest with NFL Week 10 betting. There are three contests pitting teams with winning records against each other, including Steelers vs. Commanders. Pittsburgh will visit the nation’s capital for the first time in eight years and Washington is favored by three points in the latest NFL Week 10 odds. Another matchup between division leaders on the NFL’s Week 10 schedule is Lions vs. Texans on Sunday Night Football, where Detroit is a 3.5-point favorite in NFL Week 10 spreads.
The third matchup of teams above .500 is Chiefs vs. Broncos (+8). Denver ended a 16-game losing streak to Kansas City when they last played in October 2023, and the Broncos have covered four of the last five games. How much should you factor the recent results of this series into your Week 10 NFL predictions and NFL betting picks? All of the updated NFL Week 10 lines are listed below, and SportsLine’s advanced computer model has all the NFL betting tips and NFL predictions you need to make the best Week 10 picks. NFL now.
The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 of the 2024 NFL season with an incredible 14-7 sports betting streak on top-rated NFL picks this year. Longer term, he has a 195-136 streak on top-rated NFL picks dating back to the 2017 season and a 49-29 streak on top-rated NFL picks dating back to Week 7 of 2022.
The model has also ranked in the top 10 on NFLPickWatch four of the last six years in straight NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who follows sports betting and betting apps has made strong profits.
Now, you’ve turned your attention to the latest Week 10 NFL odds and NFL betting lines and set betting picks for every NFL matchup. Head here to see each pick.
Top Week 10 NFL Predictions
We can tell you that one of the model’s strongest picks for NFL Week 10 is the Jaguars (+4, 47) covering the spread at home against the Vikings. Jacksonville started just 2-4 against the spread (ATS), but has since covered in each of its last three games. The Jags are now 4-1 ATS as underdogs this season, giving them the second-most coverages in those situations. On the other hand, Minnesota started out covering each of its first five games, but has had some turbulence lately. The Vikings have suffered two ATS losses in their last three games.
The Jags have found their offensive rhythm as the season has progressed, going from averaging 15 points in their first four games to 27 points in their last five. The Vikings defense has gone in the opposite direction throughout the year, playing noticeably worse recently. Minnesota allowed just 14.8 points in its first four games, but has given up 22.8 points in its last four games. Given both scoring trends and ATS trends, the model is firmly behind the underdog Jaguars. Jacksonville wins outright, according to the model, which says the Jags cover more than 60% of the time on an A-rated pick. See which other teams to pick here.
Another of your NFL Week 10 predictions: the Texans (+3.5, 49) cover at home against the Lions on Sunday Night Football. Houston has defeated Detroit in each of its last four meetings and is undefeated all-time at home against the Lions. The Texans also have a bye advantage in this game, having played last Thursday, while Detroit is in a difficult scheduling situation, playing its fourth road game in the last five weeks. The Texans are a perfect 3-0 when given more rest than their opponents since the start of last season.
The Lions’ offense has struggled recently, with 261 total yards on Sunday and 225 total yards the week before. That makes the last two games their two worst offensive results in their last 37 regular and postseason games. Houston limits big plays on defense like few others, as its 4.8 yards per play is the fourth-best mark in the league, while the team also ranks fourth in sacks. With those factors, Houston (+3.5) is predicted to hit over 50% of simulations, while Over (48.5) will hit over 50% of simulations. See what other equipment to choose here.
How to make Week 10 NFL picks
The model has also decided who wins and covers every other game on the NFL’s Week 10 schedule and just revealed four teams that win outright at least 70% of the time, potentially giving it a big day payment. You can only get all the picks for each game at SportsLine.
So what NFL picks can you confidently make and which four can’t-miss picks should you secure now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a tested computer model that has returned more than $7,000, and find out.
Week 10 NFL Betting Odds, Lines and Spreads
Get Week 10 NFL Picks at SportsLine
Thursday, November 7
Bengals vs. Ravens (-6.5, 53)
Sunday, November 10
Giants vs. Panthers – in Munich (+5.5, 41.5)
Patriots vs. Bears (-6, 39.5)
Bills at Colts (+4.5, 46)
Vikings against Jaguars (+4, 47)
Broncos at Chiefs (-8, 41.5)
Falcons at Saints (+3.5, 46.5)
49ers at Buccaneers (+5.5, 50.5)
Steelers at Commanders (-3, 45.5)
Titans at Chargers (-7.5, 38)
Jets at Cardinals (-1, 46)
Eagles against Cowboys (+7.5, 42)
Lions at Texans (+3.5, 49)
Monday, November 11
Dolphins at Rams (-2.5, 50.5)
