With three weeks left in the 2024 NFL season, three of the four AFC divisions have already been decided, but all four NFC divisions are still up for grabs. The Eagles (12-2) can become the first team to clinch a home playoff game on Sunday when they visit the Commanders (9-5) for a 1 p.m. ET kickoff. Philadelphia is favored by 3.5 on the road in the latest Week 16 NFL odds, up half a point from the opener, while the over-under is 45.5. The latest Eagles vs. Commanders are predicting sunny skies, light winds and temperatures in the mid-30s, and the Eagles have covered the spread in four of their last five games. Who should you back in that game and how should you handle your entire NFL moneyline, NFL over-under and NFL against spread picks? Before making Week 16 NFL picks and Week 16 NFL score predictions, you should check out NFL vs spread predictions, NFL over-under, and AI-powered NFL moneyline predictions SportsLine self-study.
Created with cutting-edge artificial intelligence and machine learning techniques by SportsLine’s data science team, AI predictions and ratings are generated for each game. The AI predictions are determined by statistically learning from each team’s historical data and then quantitatively evaluating the strength of the opponent’s defense by assigning a numerical value out of 100 called the matchup score.
Once a prediction is formulated, the AI score is generated using the prediction, matchup score, and market odds. For example, you might see an A grade on an overbet if a team faces a poor defense, their prediction differs from the line, and there are favorable odds.
Additionally, SportsLine AI is SportsLine’s first fully automated predictive model. It is continually updated with the latest available data and can help you spot the biggest discrepancies in your lines. SportsLine’s AI PickBot has reached a whopping 2,131 4.5 and 5 star prop picks since the start of last season. Anyone who has followed him is way up there on their best sports betting app and favorite betting sites.
For Week 16 NFL betting, AI PickBot evaluated NFL odds and provided NFL betting picks for all 16 games. You can only see the AI predictions for the NFL Week 16 schedule here.
Top NFL AI Picks of Week 16
After analyzing each Week 16 game, AI PickBot says the Cowboys are comfortably covered as 4-point home underdogs against the Buccaneers on Sunday Night Football in a game with an over-under of 48.5, up 1.5 from the opener. After entering the season with Super Bowl aspirations, Dallas skidded midseason with a five-game losing streak, but the franchise has shown some struggle of late.
Cooper Rush has led the team to wins in three of four, including outright underdog victories against the Commanders and Panthers. Dallas’ running game has come alive with Rico Dowdle emerging from a shared time in the backfield as the most productive running back on the roster. Dowdle has rushed for at least 100 yards in three consecutive games, becoming the first undrafted running back to do so since Arian Foster in 2014.
The Buccaneers rank 22nd in the NFL in yards allowed per carry (4.5), so we could see another strong dose of Dowdle on Sunday. Cowboys receiver CeeDee Lamb also participated fully in practice this week despite a shoulder injury. That’s part of the reason why AI PickBot rates a Cowboys cover an A+ pick and also predicts a 35-29 outright win on average for Dallas. Check out his other Week 16 football predictions and picks at SportsLine.
How to make Week 16 NFL picks
Additionally, AI PickBot has generated 16 highly coveted A+ picks for Week 16. You should check out AI PickBot’s NFL picks before placing your own Week 16 NFL bets. You can only see them at SportsLine.
Who wins and covers every Week 16 NFL game and which A+ picks should you target next? Visit SportsLine now to see the top NFL picks against the spread, over-under and moneyline, all from SportsLine’s self-learning PickBot AI that has produced 2,131 top-rated picks since the start of last season.
