The Los Angeles Rams and San Francisco 49ers will meet in a key NFC West matchup on Thursday night. Los Angeles, who beat San Francisco, 27-24, in Week 3, will try to sweep the season series with the 49ers for the first time since 2018. The Rams (7-6), second in the NFC West, come from a 44-42 victory over the Buffalo Bills last Sunday. The 49ers (6-7), tied for third place in the division with the Arizona Cardinals, defeated the Chicago Bears, 38-13, last week.
Kickoff from Levi’s Stadium in Santa Clara, California, is scheduled for 8:15 p.m. ET. The 49ers are three-point favorites in the latest Rams vs. 49ers, while the over-under for total points scored is 49.5. The 49ers are -156 moneyline favorites, while the Rams are +131 underdogs. Before making any Rams vs. 49ers, be sure to check out the NFL predictions and betting tips from SportsLine’s proven computer model, as well as everything else SportsLine has to help you crush your Thursday Night Football picks.
The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 15 of the 2024 NFL season with an incredible 25-11 betting streak on top-rated NFL picks this year. Longer term, he has a 205-139 streak on top-rated NFL picks dating back to the 2017 season and a 59-32 streak on top-rated NFL picks dating back to Week 7 of 2022.
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In addition to the model picks for this game, you can get AI props, Las Vegas expert picks, DFS Optimizer lineups, and everything you need to crush your Thursday Night Football bets. Go to SportsLine now to see it all.
Now, the model has set his sights on Rams vs. 49ers and just set their NFL picks and predictions. You can head over to SportsLine now to check out model picks. Here are several NFL odds and NFL betting lines for Niners vs. Rams:
- Difference between Rams and 49ers: 49ers -3
- Rams vs. 49ers over/under: 49.5 points
- Rams vs. 49ers money line: 49ers -156, Rams +131
- LAR: The Rams are 5-5 against the spread in their last 10 games
- SF: 49ers are 4-6 ATS in their last 10 games
- Rams vs. 49ers picks: See the picks at SportsLine
Top Rams vs. 49ers predictions
For Rams vs. 49ers on Thursday Night Football, SportsLine model beats total. The Over has also hit in each of the last four matchups between the Rams and 49ers, including both games last season. The Over has been correct in three of the last four games played in San Francisco. Defensively, both teams are in the bottom half of the league: San Francisco allows 23.7 points per game, while Los Angeles allows 25.5.
Both offenses clicked on Sunday, combining to score 82 points in their wins over the Bills and Bears. San Francisco quarterback Brock Purdy was on fire against Chicago, completing 20 of 25 passes for 325 yards and two touchdowns. Los Angeles quarterback Matthew Stafford completed 23 of 30 passes (76.7%) for 320 yards and two touchdowns against Buffalo.
In two of the last three meetings between the Rams and the 49ers, they have combined for 51 or more points. In the Week 3 matchup, Purdy completed 22 of 30 passes for 292 yards and three touchdowns. Meanwhile, Rams running back Kyren Williams had a big game, rushing 24 times for 89 yards and two touchdowns. He also caught two passes for 27 yards and a score. See which side to choose here.
How to make Rams vs. 49ers picks
In addition to going over, it also says that one side of the differential affects more than 50% of the simulations. You can only get the NFL model picks at SportsLine.
So Who Wins Rams vs. 49ers on Thursday Night Football and which side of the spread wins more than 50% of the simulations? Visit SportsLine now to see which side of the Rams vs. 49ers jump, all from the advanced model that goes well over $7,000 on their NFL picks, and find out, and don’t forget to check out the AI accessories, expert in Las Vegas. picks, DFS Optimizer lineups and all the other tools to crush your TNF picks at SportsLine.
